Randy Moss's Cancer

Randy Moss. Source: Shutterstock
Who is Randy Moss?
Randy Moss, 48, is a National Football League (NFL) Hall of Famer who played for 14 seasons. After concluding his career on the field, Moss moved to ESPN, where he worked as an analyst for the Sunday NFL Countdown and Monday Night Countdown.
Randy Moss’s health
In December 2024, Randy Moss announced that he would take an extended leave of absence from his ESPN role for health reasons. In a following statement, the network announced that Moss would have their full support during this period.
Randy Moss’s cancer
Moss was diagnosed with stage 2 bile duct cancer, a rare type of cancer. The bile ducts are a network of tubes that connect the flow of digestive fluid between the liver, gallbladder and small intestine.

Bile duct location in the digestive tract. Adapted from: Shutterstock
Following that, Randy Moss announced via Instagram that he had undergone the Whipple procedure to treat the cancer. The Whipple procedure is a surgery that removes part of the pancreas, small intestine, bile duct and gallbladder. He was in the hospital for nearly a week after his surgery.
Randy Moss cancer update 2025
In September 2025, Randy Moss did an interview with Good Morning America about his fight with cancer.
Here, Moss shared that he was diagnosed with cancer after experiencing symptoms including dark-colored urine and yellow eyes from jaundice. He was in good health before, and admitted that he was shocked to receive the diagnosis, saying that it “hit like a ton of bricks”.
Randy Moss’s interview with Good Morning America. Source: Youtube/@GMA
Fortunately, on 7 September 2025, Randy Moss announced on ESPN that "All my treatment is over, ringing the bell, now I'm back with the family, man."
His wife, Lydia Moss, was his primary caregiver as he recovered from the disease. She revealed some challenges through this journey, sharing that "It was hard for me, because he didn't want our help, because he's used to doing everything on his own.”
With her support, she played a big role in Moss’s cancer recovery. She pushed to connect with him, and said "I was kicking down them doors. I was opening up those blinds. I was like, 'Even if I just have to sit here, I'm just gonna sit here. Even if you angry, even if you don't wanna talk, we gonna be here.'"
Currently, Moss is raising awareness and funds for cancer research through the “Let’s Moss Cancer” campaign.