Uterine Cancer: Prevention

Uterine cancer occurs when abnormal cells in the lining of the uterus grow uncontrollably. While there is no guaranteed way to prevent uterine cancer, certain strategies can help lower the risk.

Body weight and estrogen

Obesity is one of the most important risk factors. Excess body fat increases estrogen levels, which can stimulate the uterine lining and increase cancer risk.

Diet

A balanced diet can help maintain a healthy weight. Diets high in processed foods and excess calories may contribute to weight gain, while diets rich in fruits, vegetables, and whole grains support overall health.

Physical activity

Regular exercise helps maintain a healthy weight and may reduce cancer risk. Aim for at least 150 minutes of moderate activity or 75 minutes of vigorous activity weekly, along with strength training.

Birth control pills can reduce the risk of endometrial cancer by about 30% or more. However, they also carry risks and should be discussed with a healthcare provider.

Estrogen-only therapy increases risk in women with a uterus, while combined estrogen-progestin therapy reduces this risk. However, there are other health considerations when determining the type of hormone therapy.

Routine screening for uterine cancer is not recommended for most people. However, some individuals have a higher risk due to inherited conditions. These include:

• Lynch syndrome
• Cowden syndrome
• Strong family history of uterine or colorectal cancer

Genetic testing and counseling may help assess risk and guide preventative strategies.

• Maintain a healthy weight
• Stay physically active
• Eat a balanced diet
• Discuss medications and hormone therapy with your doctor
• Consider genetic counseling if you have a strong family history

While these strategies can lower the risk of uterine cancer, they do not eliminate it completely. A personalized approach based on your health, risk factors, and medical history is most effective. If you have concerns about your risk, discuss them with a healthcare provider to determine the best preventive strategies for you.